منابع مشابه
Plasma proteome analysis: 2D gels and chips.
The knowledge of concentration, modification and interaction of proteins is fundamental in determining the phenotype of living organisms. Plasma, the primary clinical specimen, contains numerous and diverse proteins. The functions of these proteins are as manifold as the diversity of the protein themselves. Many of them have been largely used for many years as biomarkers of diseases and indicat...
متن کاملGlobal analysis of protein activities using proteome chips.
To facilitate studies of the yeast proteome, we cloned 5800 open reading frames and overexpressed and purified their corresponding proteins. The proteins were printed onto slides at high spatial density to form a yeast proteome microarray and screened for their ability to interact with proteins and phospholipids. We identified many new calmodulin- and phospholipid-interacting proteins; a common...
متن کاملMesoporous silica chips for selective enrichment and stabilization of low molecular weight proteome.
The advanced properties of mesoporous silica have been demonstrated in applications, which include chemical sensing, filtration, catalysis, drug delivery and selective biomolecular uptake. These properties depend on the architectural, physical and chemical properties of the material, which in turn are determined by the processing parameters in evaporation-induced self-assembly. In this study, w...
متن کاملBig Chips
scaling (that is, Dennard scaling) provided three benefits: doubling of integration capacity to deliver twice the number of transistors per unit area every two years at constant price, increased transistor performance, and reduced energy per transistor. With the steady erosion of the latter two benefits, the low-hanging fruit for performance increase has been to exploit integration capacity via...
متن کاملPNA Chips
Definition Peptide nucleic acid (PNA) is an artificial mimic of nucleic acid, which was invented more than a decade ago (7). The molecule combines many features that are similar to those of natural nucleic acids with characteristics that are rather different or even unique to PNA. First and foremost, N-(2-aminoethyl)-glycine units linked by ▶amide bonds substitute the (deoxy)ribosephosphate bac...
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ژورنال
عنوان ژورنال: Genome Biology
سال: 2001
ISSN: 1465-6906
DOI: 10.1186/gb-spotlight-20010727-01